I do use airplane mode twice a day. My commute to work takes me underground, where no signal is available. In an effort save a little juice, i shut off mobile connection before getting into the subway instead of having the phone search for a signal. I'm no doctor, but at least that what I think is happening.
Also at night, before bed I put it on airplane mode as I'm not a fan of getting notifications of emails, facebook, etc. at all hours of the night. Even with the ringer off, the vibration on my nightstand is enough to wake me.
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