Whoa Tex lol
I've never needed juice defender on my Desire or XE, why do you need it?
And ive no experience of android booster, again why do you need it.?
I have no apps I don't use running in the background from startup, use your task manager to kill them and see if they start up again. Check what apps you've got set to run on startup and maybe use system panel app to monitor and kill. Make sure GPS and WiFi are only set to come on when you want them. Look at my homescreen shots, in other thread, and try extended controls to access GPS and WiFi easily.
No idea what I'm doing, but I like pressing buttons