The root tool for the EVO Design does have a De-Sense option, but some bugs are being worked out. The Gallery has no alternative so when Sense is disabled, there's no picture viewer is one of the biggest complaints at the moment.
Samsung Galaxy S® 4 MJA Rooted with CF Auto-Root Tutorial
HTC EVO Design 4G™ v4.0.3 Bootloader Unlocked & Rooted with HTC SuperTool v3
If it ain't broke, use a sledge hammer.