The rectangular, predominantly symmetrical nature of most smartphones means if you're not looking, you might find you're holding the handset the wrong way around when a call comes in. Google's most recently awarded patent may seek to end your orientation confusion by adding a microphone and speaker at both ends of the device. That way, when you pick it up to answer a call, it'll determine which way you're holding it and select the microphone and speaker accordingly.
Dear god, no.
In the first place, I am pretty sure that we'd all notice if the writing were upside down when deciding to answer that long call from Aunt Fanny.
In the second place, aesthetics everywhere used to standing on their heads in meditation and calling Aunt Fanny back to fight the boredom while the blood rushes to their brains are not going to be happy with this at all.
This is one of the worst answers to a question that no one's asked that I've ever seen.
BTW - if there are people that can't tell which end of the phone is up - leave them be. The world is better off not hearing them.