Originally Posted by Ballymoss
Since you do it yourself, how safe it is partly down to the quality of the components you use but largely to how good a plumber you are.
Water cooling the RAM looks great but is largely unnecessary, cooling the GPU brings benefits but voids the warranty.
Having said that, the moment when you power it up and it works is quite a rush!
Not sure on other companies, but taking off the stock cooler and using a GPU waterblock WOULD NOT void EVGA's warranty unless there was water damage. All we require is that if you have to send it in for RMA, you remove the waterblock and reinstall the original heatsink. Or for those who don't want the hassle, we usually produce a limited quantity of high end cards in a series with our own custom blocks already in place.