There is another fix on the xda site without the need to install another ROM.
"for those of you who are experiencing irresponsive back/home buttons you could try this below:
go to settings -> language&keyboard ->HTC sense input -> advanced -> calibration tool
When you're calibrating the keyboard, press the keys very lightly, after you're done you should have a better back/home key response."
worked for me.
Credit to mingtaoh