Originally Posted by joesixpack
I don't think there is (since it's a hardware feature) but I could be wrong. Besides, why would you want to disable it? At least you'll save some wear on the power button by using the Home button to wake it up. I've read that these buttons have a limited life, so I'll take any opportunity I can to conserve the power button's life.
Now if they would only give us the option to use the volume buttons to wake the phone...
On my S4 Active, carried in my left front pocket, twice now the Home button has turned on the screen, and my leg (through the pocket material) has been enough to use the EMERGENCY call function. Had 911 call me back asking if there was an emergency and my Mom as well (she's an 'emergency contact'). If only the side power button would turn on the screen, I'd have no issue. I need to de-activate that HOME button for screen wake.