Ktweaker app doing great for me syd so
try clearing ktweaker cache+data and remove ktweaker entry in the supersu app and reboot, then configure ktweaker again.
I think I just won the "how many times can you use the word ktweaker in a single sentence" competition.
Kernelwipe will remove all your profiles, so save them somewhere else first. They are in /sdcard/KTweaker