I loved the SenseUI at first, but it's not REALLY necessary. Beautiful Widgets gives the nice clock / weather home screen, and with App Organizer you can fit all your apps cleanly on your 3 home screens, leaving plenty of room for widgets without bloating or crowding any of the screens (and thus giving your background wallpaper a chance to get noticed)
My home screens consist of:
Left: Pandora Widget up top, 4 apps along the bottom (App Organizer "All Folders", Camera, Gallery, Settings)
Mid: Beautiful Widgets Home, 4 apps along the bottom (Phone, Visual VM, Browser, Market)
Right: Pure Calendar Agenda, 4 apps along the bottom (Gmail, Maps, DocumentsToGo Recently Used, App Organizer "Starred Apps")
I'm not sure what I would do with 7 screens...