I've gone through the Verizon silicone, the Body Glove, and am now using the Innocase II.
The silicone was OK, but I needed more protection. I'm a commercial service tech and I go in some pretty harsh environments... I was afraid I'd break the phone even with the case. I returned it and got the Body Glove, which I hated from the first minute. The thing is HUGE. The grippiness (I don't think that's even a word) was nice, but the bulk was intolerable. It made it very difficult to use the edges of the screen or the trackpad. I don't know if it was just the one I had, but the corner latches started turning loose after about a week. I returned it and got the Innocase II/holster combo. I love it. The first one I had was from the bad run which had the looseness issues. They replaced it with no problem and the new one is great.
I'm still a little nervous about the level of protection in my line of work, but I think it should provide plenty of protection for someone who doesn't endanger their equipment. I'm currently waiting for my Innocase Rugged to arrive.
ETA: I know lots of folks who have and LOVE Otterboxes. I waited for them to come out with their cases but I'm sick of waiting. I need a tough case NOW. If they'd been on the ball, I'm fairly confident that I'd be using their product instead of Seidio's.