I've had my droid since launch, and today is the first day that I had any issue. I was driving to an unknown place, and suddenly...the thing FREAKED out!! Started just rambling...."make a U turn, turn left onto ....proceed for 50 miles, make a left in Montana...(I'm in Ohio) Really, the thing had a nervous breakdown. I had to pull over, turn off the phone and start up navigation again. After that it was fine, but for a few minutes there I could have ended up in Siberia!!
On my way back, I had a thought though...when it went nuts, I was driving parallel to a large airport. However, when I drove back via the same route, the system did not flake out on me.
ps...this happened at about 12pm EST