Nah, you should be OK. Be cautious around the ports that you don't get a drip in as even brief liquid exposure could cause problems, but if you are just wiping the surface you should be OK.surface of the mobile phone
Do I need to avoid area near ports and speakers
In applying screen protectors to my phone, small alcohol prep wipes are usually included for cleaning the screen first. I wouldn't make a habit of using alcohol, though. Vinegar has been used for thousands of years to clean things: in fact, we use a household glass cleaner based on vinegar (not toxic ammonia). Instead of alcohol, try a microfiber cloth and a little distilled white vinegar.
I have tried the alcohol wipes that come with screen protectors, and also the thing they give to wipe afterwards, with poor results.
I always had to use a microfiber after the included cleaners, and then finish with a 100% cotton cloth that has NEVER been washed with any type of fabric softener, dryer sheets included (They all leave wax in cloth, which makes them non absorbant, causes them to smear when wiping glass, and ruins flame retardency as well!) In fact, the cloths I use for such things are hung to dry, I do not even use the dryer for them.
My screens are completely pristine before I place the protecters on.
Also note that microfiber cloths will leave tiny fibers behind, especially if used dry.
That is fine for everyday use, but for things like screen protector installation I always finish with a 100% cotton cloth dedicated to this purpose (and my eyewear in the meantime).
You may be overreacting. A lot of cloth specially designed for eyewear is made of microfiber