I checked the online support for Chromecast and there is no mention of the ability to install the device in a Receiver/Amplifier. All devices run through my receiver which is my switcher to play all audio and route the appropriate video to my TV. I believe this will be common for many since TV speakers are poor. Tonight I plan to install the Chromecast into an HDMI port on my receiver to see if it works. If it works this will make use of my Bose speakers and surround setup. Anyone else doing this?