Might wanna check out this thread...

http://androidforums.com/motorola-droid/79910-launcherpro-better-than-helix-you-judge.html

BTW...to answer your question, I'm running on NexBeast and it works just fine. I think it will work on every ROM (I haven't heard different).

 

I'm using BB1.0 with LauncherPro, and it is lightning fast and does not slow down in the slightest. Been using it for the last couple of days without a single forceclose. Was using Helix before. LauncherPro is many times better and faster.

 

I'm using it over JRummy's latest stable build with bekit standard voltage kernel @ 1000 and it's as if there's a different ROM running -- all lagging experienced on Helix, Launcher or Home is eliminated --

I've also noticed a marked decrease in CPU temperature since I installed it -- not sure if that makes any sense, but it's the only thing I changed....

 

I have been jumping back and forth between LauncherPro and ADW. Both are giving me great performance but I do like prefer ADW features at this point. Neither launcher has given me any issues with lagging.

 

Just flashed to BB 1.0 last night and installed LauncherPro right away and have had no problems with them, it's a lightning fast pair.

 

If anything, LauncherPro has enhanced my Bugless Beast (NexBeast) experience exponentially. It won't slow down your phone. Quite the opposite; it will speed that sucker up.

By the way, what have you got to lose? Download it, install it, try it. If you don't like it, uninstall it.

 

Is it in the market?

 

Yes, just incase you haven't been tempted to look already.
Working great with BB V1 on my droid. Never lookin back to Helix or Home++