Help HTC Sense stopped unexpectedly

i have recently been getting this message

"the application htc sense (process has stopped unexpectedly"

i have seen plenty of posts around the net relating to but few mentioning .cs.
I have a desire HD running 2.2.1 software 1.72.405.3
this is happening everytime i unlock the phone and when i run alot of apps.
i have found that if i disable htc sense sync then it doesnt happen.
i have uninstalled all apps that have been installed recently but still no fix.

i like htc sence and would prefer to keep sync active, so if anybody could help i would very much appreciate it.