Not without rooting and installing a AOSP (?) rom over it. From what I understand about Touchwiz, lots of the little things behind the scenes still run nicely when you're using Launcher Pro instead of the Touch wiz launcher.
I could be wrong but something about swiping one way on a contact's name will send a message and swiping the other way will call them, as well as swiping the notification bar to control brightness. If I'm wrong disregard but if I'm right I don't see a need to completely get rid of Touchwiz when you're getting the best of both worlds.
The functions that you are talking about can still be used with Launcher Pro running. Like the swype to message and call. That is in the contacts part and Launcher Pro just messes with the Home screens and app tray nothing more. Your shortcuts to the toggle stuff when you pull down the notification bar will still be there.
I get what you are saying though.
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