There are so many variables and attack vectors there can be no guarantee. Flashing a stock Samsung ROM, when done properly and there are no other problems involved, will leave the data partition as is. Flashing the ROM will remove the exploit when it involves the operating system. But if the exploit resides in that data partition, it will just re-infect the OS again. In that instance, re-flashing the ROM and a Factory Reset are required. If the exploit is part of the back up you made before the Factory Reset, once you do a restore of your data that adds the exploit back to your phone. At this point you need to go through the entire sequence again, and be sure to thoroughly scan all the contents of your backed up files (with the added point being there is no anti-virus/anti-malware utility in existence that has a 100% success rate at detecting and fixing compromised files.)
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