What, specifically? You have HTC Sync already on your device. Just download the PC client from HTC and Sync your device that way.
If you're running Windows 7, do a search for XP/Vista drivers for HTC Sync and your Windows 7 OS. There are a slew of threads already covering that conundrum.
If you're trying to Sync your device with Microsoft's Office 2010 Beta, then you might run into some problems as that software is still beta and is not recognized by HTC Sync.